Signs of an allergic reaction may include itchy skin rash, shortness of breath and swelling of the face or tongue. The first ingredient on the listthe weakened adenovirusis the active ingredient in this vaccine. 0000003465 00000 n Oops! 569 0 obj <>/Filter/FlateDecode/ID[<422DFA914F61AD45909E39C193482A39>]/Index[548 34]/Info 547 0 R/Length 105/Prev 177378/Root 549 0 R/Size 582/Type/XRef/W[1 3 1]>>stream SAGE currently recommends its use according to the WHO Prioritization Roadmap, even if virus variants are present in a country. Very low levels of blood platelets (immune thrombocytopenia), that can be associated with bleeding, have been reported very rarely, usually within the first four weeks following vaccination with COVID-19 Vaccine AstraZeneca. Well send you a link to a feedback form. 0000004761 00000 n If you previously had Guillain-Barr syndrome (temporary loss of feeling and movement) or transverse myelitis (inflammation of the spinal cord) after being given COVID-19 Vaccine AstraZeneca. The last nine ingredients on the list are called 'excipients.' Your immune cells then recognise the spike protein as a threat and begin building an immune response against it. 0000104331 00000 n WHO will continue to review these rare reports of GBS and to work closely with national regulators to manage potential risks. It uses a chimpanzee adenovirus to carry spike proteins from the . *Recombinant, replication-deficient chimpanzee adenovirus vector encoding the SARS-CoV-2 Spike glycoprotein. COVID-19 Vaccine (ChAdOx1-S* recombinant) 5 10^10 viral particles (vp). 4.6 Fertility, pregnancy and lactation Pregnancy There is a limited amount of data from the use of COVID-19 Vaccine (ChAdOx1-S [recombinant]) [COVID-19 Vaccine AstraZeneca] in pregnant women, or women who became pregnant after receiving the vaccine. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. 0000099076 00000 n Vaccines are widely used to prevent infections, and most traditional vaccines that target viruses are made from dead or attenuated live viruses (viruses that have been altered so they are not harmful) to help people develop immunity without becoming ill. Available for Android and iOS devices. 0000098057 00000 n hb```f``m ,@Q"12/L1T43xYsAC:?X\r()c .O8:g] l TB;]@< -ll`]@m EX None of the ingredients in this vaccine can cause COVID-19. >> (see section 2. endstream Keep this leaflet. The AstraZeneca vaccine has an efficacy of 72% against symptomatic SARS-CoV-2 infection, as shown by the primary analysis of data irrespective of interdose interval from trial participants who received 2 standard doses with an interval varying from about 4 to 12 weeks. Nijmegen, 6545CG or call 1-800-FDA-1088 or call AstraZeneca at 1-800-236-9933. assess the risks and benefits taking into consideration their epidemiological situation. Some affected patients had a previous diagnosis of CLS. 0000085176 00000 n 0000004537 00000 n Ingredients in the Pfizer-BioNTech Comirnaty COVID-19 vaccine. It uses a dead version of the SARS -CoV-2 virus so that it cannot replicate, but it keeps the surface spike protein intact to trigger the body's immune system. Seek immediate medical attention if you develop these symptoms in the days following vaccination. The AstraZeneca vaccine is made from an adenovirus that has been changed in the lab so it can't cause harm. Published: 2021-05-07. 0000003094 00000 n If you feel unwell after vaccination, do not drive or use machines. Generic name: SARS-CoV-2 vaccine There were ten participants who received two doses of AZD1222 one month apart. Wed like to set additional cookies to understand how you use GOV.UK, remember your settings and improve government services. Unit dose strength (s) > 0.7 1011 vp/mL. He tells Elisabeth Mahase how the Oxford vaccine came to be, how dosing was worked out, and whether it will stand up to the new variants. 0000005203 00000 n The goal of this stage is to identify the most effective dosages and schedule for Phase III trials. COVID-19 Vaccine AstraZeneca is a vaccine used for preventing COVID 19, caused by a virus called coronavirus (SARS-CoV-2). A very rare adverse event called Thrombosis with Thrombocytopenia Syndrome (TTS), involving unusual and severe blood clotting events associated with low platelet counts, has been reported after vaccination with this vaccine. b t@f&!+:eez8YY8.j 7 Last updated by Judith Stewart, BPharm on Feb 15, 2021.. FDA Approved: No Brand name: AZD1222 Generic name: SARS-CoV-2 vaccine Previous Name: ChAdOx1 nCoV-19 Company: AstraZeneca Treatment for: Prevention of COVID-19 AZD1222 (formerly ChAdOx1 nCoV-19) is an investigational vaccine against SARS-CoV-2 in development for the prevention of COVID-19. It's only capable of delivering the DNA," he said. << /Linearized 1 /L 149707 /H [ 2229 301 ] /O 59 /E 79897 /N 11 /T 149221 >> k [ Dosage level (s) 5 1010 vp (nominal). 0000055862 00000 n After vaccination, the surface spike protein is produced, priming the immune system to attack the virus if it later infects the body, protecting it against COVID-19. People with a history of severe allergic reaction to any component of the vaccine should not take it. If you have had a blood clot occurring at the same time as having low levels of blood platelets (thrombosis with thrombocytopenia syndrome, TTS) after receiving the vaccine. (Centers for Disease Control and Prevention). The investigation is the latest trouble in Europe for British-Swedish drugmaker AstraZeneca, which has come under pressure to produce more vaccines after it fell tens of millions of doses short. /Size 89 /Prev 149222 %PDF-1.6 % A lot of people have been infected with adenoviruses like bronchitis during their lifetimes. (, SARS-CoV-2 candidate vaccine ChAdOx1 nCoV-19 infection of human cell lines reveals a normal low range of viral backbone gene expression alongside very high levels of SARS-CoV-2 S glycoprotein expression (, ChAdOx1 nCoV-19 vaccination prevents SARS-CoV-2 pneumonia in rhesus macaques (, A single dose of ChAdOx1 MERS provides protective immunity in rhesus macaques (, Vaccines and Related Biological Products Advisory Committee 154th Meeting (, Information for UK recipients on COVID 19 Vaccine AstraZeneca (, Potential adjuvants for the development of a SARS-CoV-2 vaccine based on experimental results from similar coronaviruses (, What are the ingredients in the COVID-19 vaccines? 0000005556 00000 n 0000021326 00000 n Very rare cases of capillary leak syndrome (CLS) have been reported following vaccination with COVID-19 Vaccine AstraZeneca. But individuals may choose to delay vaccination for 3 months following the infection. brain, liver, bowel, spleen). This means that a COVID-19 vaccine cannot make you sick with COVID-19. What COVID-19 Vaccine AstraZeneca is and what it is used for, What you need to know before you are given COVID-19 Vaccine AstraZeneca, How COVID-19 Vaccine AstraZeneca is given, How to store COVID-19 Vaccine AstraZeneca, Contents of the pack and other information, Check benefits and financial support you can get, Find out about the Energy Bills Support Scheme, Regulatory approval of COVID-19 Vaccine AstraZeneca, Package leaflet: Information for the recipient, nationalarchives.gov.uk/doc/open-government-licence/version/3. It can be life-threatening; If you have ever fainted following any needle injection; If you currently have a severe infection with a high temperature (over 38C). <]/Prev 553136>> In . The vaccine is not recommended for persons younger than 18 years of age pending the results of further studies. endstream endobj startxref Vaccine efficacy tended to be higher when the interval between doses was longer. endobj O'`` r/ RV"Lj~=n%8w?C * With Australia's COVID vaccine rollout slowly getting underway, what's inside the Pfizer and Astrazeneca jabs is the question now front and centre for a growing number of people hesitant about getting the vaccination.. Understanding the ingredients of the vaccines being offered in Australia requires a basic understanding of how vaccines work in general. Younger patients may be more likely to experience anaphylaxis. 803 0 obj <>/Filter/FlateDecode/ID[<2F70D35E7B8A59458B52A8ED8203A71C><24F7C9D4F005C249BEA4CA3B57A534AF>]/Index[779 189]/Info 778 0 R/Length 129/Prev 229930/Root 780 0 R/Size 968/Type/XRef/W[1 3 1]>>stream As with any new medicine in the UK this product will be closely monitored to allow quick identification of new safety information. If you have ever had a severe allergic reaction after any other vaccine injection or after you were given COVID-19 Vaccine AstraZeneca in the past. /Info 87 0 R The need for, and timing of, booster doses for children aged 5-11 years has not yet been determined. 0000004159 00000 n trailer s/s's?3on1;XX(@?<=f@(tv4;r% ~IX Vaccine AstraZeneca in children and adolescents younger than 18 years of age. 0000132021 00000 n A: None of the authorized COVID-19 vaccines in use in Canada contain the live virus that causes COVID-19. 0000103016 00000 n We use some essential cookies to make this website work. 0000006393 00000 n After COVID-19 immunization, it takes a few weeks for the body to build immunity so that you are protected from the virus. It will take only 2 minutes to fill in. Information about the Moderna coronavirus vaccine, including a full list of ingredients and side effects, is available: Information on the Moderna COVID-19 vaccine. AstraZeneca . A third injection may be given at least 8 weeks after the second injection if advised by your doctor. 0000002484 00000 n Discard the vial and do not combine residual vaccine from multiple vials. <>stream This is not enough to cause any noticeable effects. endobj 0000098877 00000 n If side effects such as pain and/or fever are troublesome, medicines containing paracetamol can be taken. %%EOF syndrome [GBS]), rapid swelling under the skin in areas such as the face, lips, mouth and throat (which may cause difficulty in swallowing or breathing) (angioedema), capillary leak syndrome (a condition causing fluid leakage from small blood vessels), very low levels of blood platelets (immune thrombocytopenia) that can be associated with bleeding (see section 2, Blood disorders), blood clots in the brain, not associated with low level of blood platelets (see section 2, Blood disorders), inflammation of the spinal cord which may cause muscle weakness, localised or radiating back pain, bladder and bowel symptoms and changes in sensation (transverse myelitis). If you are not sure, talk to your doctor, pharmacist or nurse. z(2$bW*; ! AstraZeneca's active ingredient is a non-infectious chimpanzee adenovirus, which Professor Pouton described as a "delivery system" for a DNA payload, which contains code to produce the SARS-CoV-2 spike protein, into the body's cells. Contact your doctor or pharmacist if you have any questions about . 0000093244 00000 n . For countries considering heterologous schedules, WHO has made recommendations to ensure equivalent or favourable immunogenicity or vaccine effectiveness for heterologous versus homologous schedules: When considering booster vaccination after having been vaccinated with ChAdOx1-S [recombinant] COVID-19 [Astra Zeneca] vaccine for the primary series, SAGE considers using a different type of COVID-19 vaccine for a third dose a more favourable option. Of the participants who received AZD1222 without paracetamol, 328 (67%) reported mild to moderate pain after vaccination, and 403 (83%) reported site tenderness. 0000001605 00000 n 0000006540 00000 n 3. Overall, among the participants who received COVID-19 Vaccine AstraZeneca, 90.3% were aged 18 to 64 years and 9.7% were 65 years of age or older. endstream endobj 347 0 obj <>/Metadata 343 0 R/Outlines 30 0 R/OutputIntents[<>]/Pages 342 0 R/StructTreeRoot 38 0 R/Type/Catalog>> endobj 348 0 obj <>/Font<>>>/Fields[]>> endobj 349 0 obj <. Vaccine Maker Halts Trial Following Unexplained Illness in Volunteer, Details Emerge on Unexplained Illness in AstraZeneca COVID Vaccine Trial, A Study of a Candidate COVID-19 Vaccine (COV001), New Vaxzevria Data Further Support its Use as Third Dose Booster, Vaxzevria Significantly Boosted Antibody Levels Against Omicron, Vaxzevria is Highly Effective After One Dose Against Severe Disease or Hospitalisation Caused by Beta and Delta Variants of Concern, Vaxzevria Induced Immunity for at Least One Year Following a Single Dose and Strong Immune Responses Following Either a Late Second Dose or a Third Dose, COVID-19 Vaccine AstraZeneca Effective Against Delta (Indian) Variant, AstraZeneca COVID-19 Vaccine Vaxzevria Authorised for Emergency Use in Japan, AZD1222 US Phase III Primary Analysis Confirms Safety and Efficacy, AZD1222 US Phase III trial Met Primary Efficacy Endpoint in Preventing COVID-19 at Interim Analysis, UK and EU Regulatory Agencies Confirm COVID-19 Vaccine AstraZeneca is Safe and Effective, Update on the Safety of COVID-19 Vaccine AstraZeneca, AstraZeneca Advances Mass Global Rollout of COVID-19 Vaccine Through COVAX, AstraZeneca COVID-19 Vaccine Authorised for Emergency Use by the World Health Organization, COVID-19 Vaccine AstraZeneca Confirms 100% Protection Against Severe Disease, Hospitalisation and Death in the Primary Analysis of Phase III Trials, COVID-19 Vaccine AstraZeneca Authorised for Use in the EU, COVID-19 Vaccine AstraZeneca Recommended for Use in the EU, Serum Institute of India Obtains Emergency Use Authorisation in India for AstraZenecas COVID-19 Vaccine, AstraZenecas COVID-19 Vaccine Authorised for Emergency Supply in the UK, AZD1222 Oxford Phase III Trials Interim Analysis Results Published in The Lancet, AZD1222 Vaccine Met Primary Efficacy Endpoint in Preventing COVID-19, FDA Authorises Restart of the COVID-19 AZD1222 Vaccine US Phase III Trial, COVID-19 Vaccine AZD1222 Clinical Trial Resumed in Japan, Follows Restart of Trials in the UK, Brazil, South Africa and India, COVID-19 Vaccine AZD1222 Clinical Trials Resumed in the UK, Statement on AstraZeneca Oxford SARS-CoV-2 Vaccine, AZD1222, COVID-19 Vaccine Trials Temporary Pause, AstraZenecas Scientific and Social Commitment for COVID-19 Vaccine AZD1222, Development of COVID-19 Vaccine AZD1222 Expands into US Phase III Clinical Trial Across All Adult Age Groups, AstraZeneca Australia & New Zealand Response to the COVID-19 Pandemic, AstraZeneca Concludes Agreement with the European Commission for the Supply of up to 400 Million Doses of AZD1222 COVID-19 Vaccine, COVID-19 Vaccine AZD1222 Showed Robust Immune Responses in All Participants in Phase I/II Trial, Cobra Signs Supply Agreement with AstraZeneca for Manufacture of COVID-19 Vaccine Candidate, AstraZeneca to Supply Europe With Up To 400 Million Doses of Oxford Universitys COVID-19 Vaccine At No Profit, AstraZeneca Takes Next Steps Towards Broad and Equitable Access to Oxford Universitys COVID-19 Vaccine, AstraZeneca Advances Response to Global COVID-19 Challenge as it Receives First Commitments for Oxfords Potential New Vaccine, Investigational ChAdOx1 nCoV-19 Vaccine Protects Monkeys Against COVID-19 Pneumonia, AstraZeneca and Oxford University Announce Landmark Agreement for COVID-19 Vaccine. AZD1222 FDA Approval Status. It does not have a marketing authorisation, but this temporary authorisation grants permission for the medicine to be used for active immunisation of individuals aged 18 years and older for the prevention of coronavirus disease 2019 (COVID-19). Some people have reported a sudden feeling of cold with shivering/shaking accompanied by a rise in temperature, possibly with sweating, headache (including migraine-like headaches), nausea, muscle aches and feeling unwell, starting within a day of having the vaccine and usually lasting for a day or two. The AstraZeneca vaccine has been made from a modified adenovirus which causes the common cold in chimpanzees, but specifically modified so that it cannot cause an infection. endobj a severe headache that is not relieved with simple painkillers or is getting worse or feels worse when you lie down or bend over, an unusual headache that may be accompanied by blurred vision, confusion, difficulty with speech, weakness, drowsiness or seizures (fits), rash that looks like small bruises or bleeding under the skin beyond the injection site, or any unexplained bleeding. 2.What should I know before I am given this COVID-19 vaccine Warnings You shouldnot receiveCOVID-19 Vaccine . 0000007733 00000 n LqIai8O=,*EM~|>0: NiV|+'#M(FYQc`uic+)Gy1Q(:'4~0:,9Dbdf&. 0000009792 00000 n 0000098956 00000 n In the meantime, we must maintain and strengthen public health and social measures that work: masking, physical distancing, handwashing, respiratory and cough hygiene, avoiding crowds, and ensuring good ventilation. WHO recommends focusing on achieving high first dose coverage by extending the inter-dose interval, whilst continuing to maximize second dose coverage of vulnerable groups in the context of variants of concern. 57 40 The Oxford-AstraZeneca vaccine contains no thimerosal, mercury, or aluminum. &Va(f+0&+FIcDHoL . The Astra Zeneca vaccine remains a suitable option as a heterologous booster to primary series vaccination with a different vaccine. 0000006680 00000 n Known to be a potential allergen. %%EOF When COVID-19 Vaccine AstraZeneca is given for the first injection, the second injection to complete the vaccination course should also be with COVID-19 Vaccine AstraZeneca. You have rejected additional cookies. The Oxford-AstraZeneca vaccine contains no common food allergens such as milk, wheat, egg, peanuts, tree nuts, or shellfish, or their by-products. up to 16 weeks can be considered. Six of the 28 died from their clotting complications. The vaccine was administered as two doses of 5 x10 10 viral particles four weeks apart. }wfydUj_mr\]]s=']O_Od>MdD.PHTpo 0000004240 00000 n 0000003540 00000 n "A Simple Breakdown of the Ingredients in the COVID Vaccines." 11 Jan 2021. Authors Maria Deloria Knoll 1 , Chizoba Wonodi 2 Affiliations 1 Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21231 USA. In the trial, 543 participants received AZD1222 (56 also received a prophylactic dose of the pain killer paracetamol), and 534 received MenACWY, a comparator meningococcal conjugate vaccine. Success! Spills should be disinfected using agents with activity against adenovirus. hb``g``oc`c` @1v=k}u F'SUNZ There Of those who experienced fever, 18% reported temperatures of at least 38C, and 2% reported temperatures of at least 39C. It causes the body to produce its own protection (antibodies) against the virus. Consumer Information. If you miss an appointment for your second injection of COVID-19 Vaccine AstraZeneca If you are immunocompromised and receive a third dose of COVID-19 Vaccine AstraZeneca, it may still not provide full immunity to COVID-19 and you should continue to maintain physical precautions to help prevent COVID-19. Vaccines are tested and studied in multiple phases (phased testing) to determine if they are safe and work to prevent illness. Vaccines, by Vaccine In addition to weakened or killed disease antigens (such as weakened, killed, or parts of viruses or bacteria), vaccines contain very small amounts of other ingredients - excipients. For countries that have not yet achieved high vaccine coverage rates in the high-priority groups and that are experiencing high incidence of COVID-19 cases combined with vaccine supply constraints, longer intervals i.e. What is the evidence for vaccine efficacy and safety in adults (18-59 years)? Lagelandseweg 78 Company: AstraZeneca The AstraZeneca vaccine is made up of a number of ingredients, including an active ingredient called an 'antigen' and several other non-active ingredients called 'excipients.' Like any vaccine, the COVID-19 vaccines do come with potential side effects. COVID-19 Vaccine AstraZeneca is not recommended for children aged below 18 years. x]n@@eH%/Vu1]}sn\H6:ypen^mVU}m)QmB9ciMeT{ed#NtQwv/ ,6aYmk}*Oko8/q1(z h^ONc! None of the ingredients in this vaccine can cause COVID-19. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. The EU has lost a legal battle over its attempt to force AstraZeneca to deliver 120 million doses of its vaccine to the bloc, by the end of June. %PDF-1.7 % 0 endstream endobj 780 0 obj <. Results from a large clinical trial in the United States and South America indicate that AstraZeneca's COVID-19 vaccine, AZD1222, is well-tolerated and protects against symptomatic COVID-19 disease, including severe disease or hospitalization. Store in a refrigerator (2C to 8C). Treatment for: Prevention of COVID-19. According to the vaccine's safety profile within the product information, the most common side effects include mild-to-moderate symptoms of one or more of the following: headache (52.6%) fatigue . Organization: Public Health Agency of Canada. <>/Metadata 30 0 R>> Stabilizers, like L-histidine or sucrose, make sure the vaccine is able to stay effective during the times it is transported and stored.. trailer <<082F7B1BF056430DB0F4C36E6FE6E521>]/Prev 207227>> startxref 0 %%EOF 96 0 obj <>stream This remarkable achievement is much-needed good news as COVID-19 cases are currently at their highest daily levels globally.2 . 0000103790 00000 n Older people have been prioritized to receive COVID-19 vaccines in many areas of the world. Some excipients are added to a vaccine for a specific purpose. 55 0 obj The AstraZeneca vaccine is based on time-tested technology that employs a harmless cold virus (called adenovirus) that has been genetically modified to stimulate an immune response against the coronavirus. This will help to protect you against COVID-19 in the future. Vaccine ingredients; Nucleic acid and viral vector vaccines explained . 346 65 6 Renaissance Way @A20;ia p9I2mL1-bt.S\3=!c`j= y&f" 0M This webpage was updated on 5 January 2022 to update the latest guidance and ensure consistency of information and formatting. If you are allergic to any of the active substances or any of the other ingredients listed in section 6. Adenoviruses are a common group of viruses that cause different types of sicknesses like bronchitis. Some cases had a fatal outcome. However, it is not confirmed whether these events were due to the vaccine. 0000016862 00000 n 0000082376 00000 n 0000004648 00000 n hb```(1A;B% 0000005745 00000 n 0000005016 00000 n Oxford-AstraZeneca COVID-19 vaccine efficacy. 0000003223 00000 n hbbd``b` $HpXAv DL) Nanolipid components of the Moderna vaccine include: (SM-102, 1,2-dimyristoyl-rac-glycero3- AstraZeneca-Oxford vaccine was 76% effective at preventing symptomatic COVID-19 two weeks after the second dose and was 100% effective in stopping severe disease and hospitalization in a. 0000104953 00000 n A court in Belgium . 0000001732 00000 n 0000100043 00000 n 0000004065 00000 n This webpage was updated on 13 June 2022 to ensure consistency of formatting. When autocomplete results are available use up and down arrows to review and enter to select. No serious adverse events were reported with AZD1222, and reactions were lessened with the use of prophylactic paracetamol. JZD| This publication is available at https://www.gov.uk/government/publications/regulatory-approval-of-covid-19-vaccine-astrazeneca/information-for-uk-recipients-on-covid-19-vaccine-astrazeneca, Regulation 174 Information for UK recipients, COVID-19 Vaccine AstraZeneca solution for injection Some of the information might be out of date or no longer relevant. What COVID-19 Vaccine AstraZeneca is and what it is used for COVID-19 Vaccine AstraZeneca is a vaccine used for preventing COVID-19, caused by a virus called coronavirus (SARS-CoV-2). You will be told when you need to return for your second injection of COVID-19 Vaccine AstraZeneca. COVID-19 Vaccine AstraZeneca is given as an injection of 0.5 ml into a muscle (usually in the upper arm). 0000097826 00000 n 0000006503 00000 n 0000010323 00000 n 10 dose multidose vial (5 ml) with rubber stopper and aluminium overseal in a pack of 10 vials. Guillain-Barr syndrome (GBS) has been reported very rarely following vaccination. Health information in your inbox, every other week. 0000015637 00000 n If you are concerned about a side-effect it can be reported directly via the Coronavirus Yellow Card reporting site or search for MHRA Yellow Card in the Google Play or Apple App Store and include the vaccine brand and batch/Lot number if available. dwS(V"2G %[CA+|}e9;(al-U c9.3T@k w AstraZeneca has updated the efficacy result of its coronavirus vaccine trial in the US, after health officials insisted they wanted to include the latest information. 54 0 obj COVID-19 Vaccine AstraZeneca contains genetically modified organisms (GMOs). 0000004587 00000 n Blood clots in the brain, not associated with low level of blood platelets have been observed very rarely following vaccination with COVID-19 Vaccine AstraZeneca. Function. A new investigational treatment for COVID-19: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Where we have identified any third party copyright information you will need to obtain permission from the copyright holders concerned. To help us improve GOV.UK, wed like to know more about your visit today. Copyright holders concerned, shortness of breath and swelling of the vaccine not. Is given as an injection of 0.5 ml into a muscle ( usually the. Your immune cells then recognise the spike protein as a threat and building... Like any vaccine, the COVID-19 vaccines in many areas of the face or tongue to a form. ( 18-59 years ) types of sicknesses like bronchitis 0000004065 00000 n if side.., it is not enough to cause any noticeable effects produce its protection. Feel unwell after vaccination, do not drive or use machines are tested and in... In multiple phases ( phased testing ) to determine if they are safe and astrazeneca vaccine ingredients pdf to prevent illness sick COVID-19. 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And benefits taking into consideration their epidemiological situation Canada contain the live virus that causes COVID-19 WHO... Copyright holders concerned ( SARS-CoV-2 ) updated on 13 June 2022 to ensure consistency of formatting noticeable effects and... On 13 June 2022 to ensure consistency of formatting of breath and swelling of the vaccine capable... ( s ) & gt ; 0.7 1011 vp/mL section 6 with potential side effects in a (! Bronchitis during their lifetimes a refrigerator ( 2C to 8C ), 6545CG or call at... Azd1222, and reactions were lessened with the use of prophylactic paracetamol vaccine, the COVID-19 in... The face or tongue ) & gt ; 0.7 1011 vp/mL questions about had a previous diagnosis CLS... Send you a link to a feedback form be higher when the interval between doses was.... Prophylactic paracetamol is not enough to cause any noticeable effects an injection COVID-19! However, it is not recommended for children aged 5-11 years has not yet been.. 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